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L002
Artikelnummer: TGM-T11807-100mg
Description: L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 µM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By blocking histone acetylation, p53 acetylation, and STAT3 activation, L002 shows...
| Anwendung: | p300 histone acetyltransferase inhibitor |
| CAS | 321695-57-2 |
| MW: | 321.35 D |
ab 34,00 €
L002
Artikelnummer: Cay17778-5
L002 is an inhibitor of p300 histone acetyltransferase (KAT3B, IC50 = 1.98 µM in vitro). It has weaker inhibitory effects against PCAF and GCN5 (IC50s = 35 and 34 µM, respectively) and is specific for p300 over a panel of additional acetyltransferases, deacetylases, and methyltransferases. L002 blocks acetylation of...
| Schlagworte: | NSC 764414, p300/CBP Inhibitor VI, 2,6-dimethyl-2,5-cyclohexadiene-1,4-dione 4-[O-[(4-methoxyphenyl)sulfonyl]oxime] |
| Anwendung: | p300 histone acetyltransferase inhibitor |
| CAS | 321695-57-2 |
| MW: | 321.3 D |
ab 111,00 €
