Zu "319460-85-0" wurden 5 Artikel gefunden!
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Axitinib
Artikelnummer: TGM-T1452-1g
Description: Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRbeta, respectively. Target: PDGFR, VEGFR, c-Kit. Smiles: C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2. References: Hu-Lowe...
| Schlagworte: | AG-013736 |
| Anwendung: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 319460-85-0 |
| MW: | 386.47 D |
ab 34,00 €
Axitinib
Artikelnummer: LKT-A9435.25
VEGFR inhibitor.
| Schlagworte: | N-methyl-2-[[3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl]sulfanyl]benzamide |
| Anwendung: | PDGFRB / VEGFR1 / VEGFR2 / VEGFR3 / c-KIT tyrosine kinase inhibitor |
| CAS | 319460-85-0 |
| MW: | 386.47 D |
ab 73,00 €
Axitinib
Artikelnummer: Cay13813-50
Axitinib is a VEGFR inhibitor (IC50s = 1.2, 0.25, and 0.29 nM for VEGFR1, -2, and -3, respectively). It also inhibits c-Kit and PDGFRbeta (IC50s = 1.7 and 1.6 nM, respectively). It inhibits VEGF-induced migration of and tube formation by human umbilical vein endothelial cells (HUVECs). Axitinib (1-100 mg/kg) reduces...
| Schlagworte: | AG-013736, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 319460-85-0 |
| MW: | 386.5 D |
ab 106,00 €
AG013736 (Axitinib)
Artikelnummer: A0927-01.100
Axitinib (also known as AG013736) is a small molecule tyrosine kinase inhibitor under development by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in...
| CAS | 319460-85-0 |
| MW: | 86469 |
ab 853,00 €
AG013736 (Axitinib)
Artikelnummer: A0927-01.10
Axitinib (also known as AG013736) is a small molecule tyrosine kinase inhibitor under development by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in...
| CAS | 319460-85-0 |
| MW: | 86469 |
ab 147,00 €
