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JNJ0966
Artikelnummer: TGM-T4783-100mg
Description: JNJ0966 is a highly selective [MMP-9 zymogen] inhibitor with an IC50 of 440 nM. Target: MMP. Smiles: COc1ccccc1Nc1nc(cs1)-c1sc(NC(C)=O)nc1C. References: Scannevin RH, et al. Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) thatallosterically inhibits zymogen...
| Anwendung: | MMP-9 zymogen activation inhibitor |
| CAS | 315705-75-0 |
| MW: | 360.45 D |
ab 54,00 €
JNJ-0966
Artikelnummer: Cay31781-1
JNJ-0966 is an inhibitor of matrix metalloproteinase-9 (MMP-9) zymogen activation (IC50 = 440 nM). It is selective for MMP-9 over MMP-1, MMP-2, and MMP-3 zymogen activation at 10 µM and does not inhibit the catalytic activity of MMP-1, -2, -3, -9, or -14. It inhibits invasion of HT-1080 cells in a MatrigelTM assay...
| Schlagworte: | N-[2-[(2-methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-acetamide |
| Anwendung: | MMP-9 zymogen activation inhibitor |
| CAS | 315705-75-0 |
| MW: | 360.5 D |
ab 48,00 €
