Zu "3133-16-2" wurden 3 Artikel gefunden!
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4-Octyl itaconate
Artikelnummer: TGM-T4580-100mg
Description: 4-Octyl Itaconate, a cell-permeable derivative of Itaconate, is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 and inhibits phosphorylation of STING. Target: Nrf2. Smiles: C(CC(C(O)=O)=C)(OCCCCCCCC)=O. References: Mills EL, et al. Itaconate is an anti-inflammatory metabolite...
| Anwendung: | Prodrug, Nrf2 stabilization |
| CAS | 3133-16-2 |
| MW: | 242.31 D |
ab 33,00 €
4-octyl Itaconate
Artikelnummer: Cay25374-25
4-octyl Itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It is hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages where it acts as a regulator of macrophage function with...
| Schlagworte: | 2-methylene-butanedioic acid, 4-octyl ester |
| Anwendung: | Prodrug, Nrf2 stabilization |
| CAS | 3133-16-2 |
| MW: | 242.3 D |
ab 55,00 €
![Itaconic acid 4-octyl ester [4-Octyl itaconate]](https://www.biomol.com/media/image/9c/9a/bb/AG-CR1-3700-M010_200x200.png "Itaconic acid 4-octyl ester [4-Octyl itaconate]")
Itaconic acid 4-octyl ester [4-Octyl itaconate]
Artikelnummer: AG-CR1-3700-M050
White powder. Soluble in DMSO (30mg/ml), ethanol (30mg/ml) or DMF (30mg/ml). Chemical. CAS: 3133-16-2. Formula: C13H22O4. MW: 242.3. Derivative of itaconate (AG-CN2-0426) with enhanced cell permeability. Prodrug that is efficiently metabolized to itaconate in cells. Potent anti-inflammatory agent. In vitro it...
| Schlagworte: | 4-Octyl ester 2-methylene-butanedioic acid, 4-Octyl methylenesuccinate, beta-Monooctyl itaconate |
| CAS | 3133-16-2 |
| MW: | 242,3 D |
ab 39,00 €
