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STF-083010
Artikelnummer: TGM-T6681-100mg
Description: STF-083010 is a selective inhibitor of the IRE1alpha endonuclease. Target: IRE1. Smiles: O=C1C=Cc2ccccc2\C1=C\NS(=O)(=O)c1cccs1. References: Papandreou l, et al. Blood. 2011, 117(4), 1311-1314.
| Schlagworte: | STF083010 |
| Anwendung: | ERN1 endonuclease inhibitor |
| CAS | 307543-71-1 |
| MW: | 317.38 D |
ab 47,00 €
STF-083010
Artikelnummer: Cay17370-5
STF-083010 is an inhibitor of the IRE1/XBP1 pathway, blocking IRE1 endonuclease activity without affecting its kinase activity after endoplasmic reticulum (ER) stress both in vitro and in vivo. STF-083010 (60 µM) reduces the splicing of XBP1 by IRE1 in the presence of thapsigargin (Cay-10522), an ER stress inducer....
| Schlagworte: | IRE1 Inhibitor I, N-[(2-hydroxy-naphthalenyl)methylene]-2-thiophenesulfonamide |
| Anwendung: | ERN1 endonuclease inhibitor |
| CAS | 307543-71-1 |
| MW: | 317.4 D |
ab 60,00 €
