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Apcin
Artikelnummer: TGM-T8561-100mg
Description: Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically...
| Anwendung: | Anaphase promoting complex inhibitor |
| CAS | 300815-04-7 |
| MW: | 438.65 D |
ab 42,00 €
Apcin
Artikelnummer: AG-CR1-3603-M005
White to off-white solid. Soluble in DMSO (20mg/ml). Cell permeable compound capable of slowing anaphase-promoting complex/cyclosome (APC/C)-dependent proteolysis, Inhibitor of the ubiquitin ligase activity of the APC/C by inhibiting substrate binding to Cdc20, Distinct mechanism of action than proTAME, Blocks...
| Schlagworte: | Anaphase Promoting Complex Inhibitor |
| Anwendung: | Cell permeable ubiquitin ligase inhibitor |
| CAS | 300815-04-7 |
| MW: | 438,7 D |
ab 99,00 €
Apcin
Artikelnummer: Cay17080-1
Apcin is an inhibitor of the E3 ligase activity of the mitotic anaphase-promoting complex/cyclosome (APC/C). Apcin competitively binds to Cdc20 and prevents substrate interaction and ubiquitylation required for continuation of mitosis. Apcin enhances the effect of the APC/C inhibitor N-4-tosyl-L-arginine methyl...
| Schlagworte: | [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-carbamic acid, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester |
| Anwendung: | Anaphase promoting complex inhibitor |
| CAS | 300815-04-7 |
| MW: | 438.7 D |
ab 40,00 €
