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(±)-Norcantharidin
(±)-Norcantharidin

Artikelnummer: TGM-T5656-100mg

Description: (±)-Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers. Target: c-Met/HGFR, EGFR. Smiles: O=C1OC(=O)C2C3CCC(O3)C12. References: Qiu P , Wang S , Liu M , et al. Norcantharidin Inhibits cell growth by suppressing the...
Schlagworte: Endothall anhydride, Norcantharidin
Anwendung: PP1 / PP2A inhibitor
CAS 29745-04-8
MW: 168.15 D
ab 38,00 €
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Norcantharidin
Norcantharidin

Artikelnummer: Cay28457-5

Norcantharidin is a demethylated form of the protein phosphatase 1 (PP1) and PP2A inhibitor cantharidin (Cay-14589) and a PP1 and PP2A inhibitor (IC50s = 9 and 3 µM, respectively). It induces cell cycle arrest at the G2/M phase and apoptosis in HepG2, Hep3B, and Huh7 human hepatoma cell lines when used at a...
Schlagworte: Demethylcantharidin, NCTD, NSC 59023, (3aR,4S,7R,7aS)-rel-hexahydro-4,7-epoxyisobenzofuran-1,3-dione
Anwendung: PP1 / PP2A inhibitor
CAS 29745-04-8
MW: 168.1 D
ab 44,00 €
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