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Ro 90-7501
Artikelnummer: TGM-T16773-100mg
Description: Ro 90-7501 is an amyloid beta42 (Abeta42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer...
| Schlagworte: | RO-90-7501 |
| Anwendung: | Abeta42 fibril assembly inhibitor, TLR3 signaling modulator |
| CAS | 293762-45-5 |
| MW: | 340.38 D |
ab 31,00 €
Ro 90-7501
Artikelnummer: Cay18881-5
Ro 90-7501 is a bi-benzimidazole compound that was first found to retard the formation of mature amyloid beta42 fibrils in a cell-based assay. Instead, extended polymeric sheets and fibrillary intermediates of amyloid beta42 accumulated in response to Ro 90-7501 treatment, resulting in reduced cytotoxicity (EC50 = 2...
| Schlagworte: | 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine |
| Anwendung: | Abeta42 fibril assembly inhibitor, TLR3 signaling modulator |
| CAS | 293762-45-5 |
| MW: | 340.4 D |
ab 121,00 €
