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NEU
BI-2865
Artikelnummer: BPS-82711-1
BI-2865 is a non-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM).1
| Schlagworte: | BI-2865, pan-KRAS inhibitor, KRAS inhibitor, |
| Anwendung: | Non-covalent pan-KRAS inhibitor |
| CAS | 2937327-93-8 |
| MW: | 465,57 D |
ab 763,00 €
BI-2865
Artikelnummer: TGM-T72062-100mg
Description: BI-2865 is a non-covalent pan-KRAS inhibitor.BI-2865 binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with KD values of 6.9, 4.5, 32, 26, and 4.3 nM, respectively.BI-2865 showed antiproliferative activity in BaF3 cells expressing KRAS G12C, G12D, or G12V mutants. BI-2865 showed antiproliferative...
| CAS | 2937327-93-8 |
| MW: | 465.57 D |
ab 228,00 €
