Zu "2922824-09-5" wurden 2 Artikel gefunden!
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GPX4-IN-5
Artikelnummer: TGM-T77755-100mg
Description: GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 µM) with antitumour activity.GPX4-IN-5 induces ferroptosis and can be used for the prevention and treatment of triple-negative breast cancer (TNBC). Target: GPX. Smiles: O=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl. References: Chen...
| Anwendung: | Covalent GPX4 inhibitor |
| CAS | 2922824-09-5 |
| MW: | 381.78 D |
ab 62,00 €
C18
Artikelnummer: Cay39432-1
C18 is a covalent inhibitor of glutathione peroxidase 4 (GPX4, IC50 = 120 nM). It inhibits the growth of MDA-MB-468, BT-549, and MDA-MB-231 breast cancer cells (IC50s = 10, 75, and 12 nM, respectively). C18 (10 and 20 µM) increases lipid peroxidation and oxidized malondialdehyde (MDA) levels in MDA-MB-231 cells, an...
| Schlagworte: | 2-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(4-fluoro-3,5-dimethoxyphenyl)-acetamide |
| Anwendung: | Covalent GPX4 inhibitor |
| CAS | 2922824-09-5 |
| MW: | 381.8 D |
ab 41,00 €
