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L-Kynurenine
L-Kynurenine

Artikelnummer: TGM-T4928-1mL

Description: L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87...
Schlagworte: (S)-Kynurenine
Anwendung: AHR ligand
CAS 2922-83-0
MW: 208.21 D
ab 31,00 €
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L-Kynurenine
L-Kynurenine

Artikelnummer: Cay11305-50

L-Kynurenine is an active metabolite of tryptophan (Cay-29600, Cay-31210). It is formed from tryptophan via tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO). L-Kynurenine binds to the aryl hydrocarbon receptor (AhR, Kd = ~4 µM) and increases the activity of ethoxyresorufin-O-deethylase (EROD) in...
Schlagworte: 3-anthraniloyl-Alanine, alphaS,2-diamino-gamma-oxo-benzenebutanoic acid
Anwendung: AHR ligand
CAS 2922-83-0
MW: 208.2 D
ab 50,00 €
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