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TRAM-34
Artikelnummer: TGM-T6186-100mg
Description: TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34(TRAM 34) is 200 to 1500-fold than other ion channels. Target: Potassium Channel,...
| Schlagworte: | Triarylmethane-34, TRAM 34 |
| Anwendung: | Membrane-permeable KCNN4 inhibitor |
| CAS | 289905-88-0 |
| MW: | 344.84 D |
ab 43,00 €
TRAM-34
Artikelnummer: Cay23385-5
TRAM-34 is a membrane-permeable inhibitor of the intermediate-conductance calcium-activated potassium channel (IKCa1/KCa3.1). It blocks IKCa1 (Kds = 20 and 25 nM for the cloned and native channel in COS-7 cells and human T lymphocytes, respectively) with 200- to 1,500-fold selectivity for IKCa1 over Kv (Kv1.1-Kv1.5,...
| Schlagworte: | 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole |
| Anwendung: | Membrane-permeable KCNN4 inhibitor |
| CAS | 289905-88-0 |
| MW: | 344.8 D |
ab 52,00 €
