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Rosuvastatin
Artikelnummer: TGM-T1676-100mg
Description: Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastatin belongs to a class of medications...
| Schlagworte: | ZD 4522 |
| Anwendung: | Targets hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] (HMGCR) |
| CAS | 287714-41-4 |
| MW: | 481.54 D |
ab 45,00 €
Rosuvastatin
Artikelnummer: Cay12029-5
Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the...
| Schlagworte: | ZD 4522,... |
| Anwendung: | HMG-CoA reductase inhibitor |
| CAS | 287714-41-4 |
| MW: | 481.5 D |
ab 76,00 €
