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3CAI
Artikelnummer: TGM-T14034-100mg
Description: 3CAI is a potent and specific AKT1 and AKT2 inhibitor, demonstrating significant inhibition of AKT in an in vitro kinase assay. It suppressed the expression of AKT direct downstream targets (such as mTOR and GSK3beta) and induced growth inhibition and apoptosis in colon cancer cells. Target: Akt....
| Anwendung: | Akt1 / Akt2 inhibitor |
| CAS | 28755-03-5 |
| MW: | 193.63 D |
ab 50,00 €
3CAI
Artikelnummer: Cay14303-1
3CAI is an inhibitor of Akt1 and Akt2 with anticancer activity. It inhibits Akt1 and Akt2 in a kinase assay in a concentration-dependent manner, but has no effect on MEK1, JNK1, ERK1, or PDZ binding kinase (PBK) when used at a concentration of 1 µM. 3CAI (4 µM) increases apoptosis in HCT116 and HT-29 colon cancer...
| Schlagworte: | 3-chloroacetyl Indole, 2-chloro-1-(1H-indol-3-yl)-ethanone |
| Anwendung: | Akt1 / Akt2 inhibitor |
| CAS | 28755-03-5 |
| MW: | 193.6 D |
ab 125,00 €
