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Vildagliptin
Artikelnummer: TGM-T1502-100mg
Description: Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine. Target: Ferroptosis, Proteasome, Apoptosis,...
| Schlagworte: | LAF237, NVP-LAF 237 |
| Anwendung: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 274901-16-5 |
| MW: | 303.4 D |
ab 31,00 €
Vildagliptin
Artikelnummer: Cay14705-10
Vildagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, Ki = 0.003 µM). It is selective for DPP-4 over DPP-2, DPP-8, and DPP-9 (Kis = >500, 0.81, and 0.095 µM, respectively). Vildagliptin (3 mg/kg) decreases plasma glucose levels and increases plasma insulin levels during an oral glucose challenge in Zucker...
| Schlagworte: | 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
| Anwendung: | DPP4 / DPP8 / DPP9 inhibitor |
| CAS | 274901-16-5 |
| MW: | 303.4 D |
ab 39,00 €
Vildagliptin
Artikelnummer: LKT-V3345.10
Inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.
| Anwendung: | DPP4 inhibitor |
| CAS | 274901-16-5 |
ab 111,00 €
