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(2R)-Octyl-alpha-hydroxyglutarate-d17
Artikelnummer: Cay19694-5
alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
| Schlagworte: | (2R)-Octyl-2-HG-d17, 2R-hydroxy-pentanedioic acid, 1-octyl-d17 ester |
| Anwendung: | Cell-permeable D-2-HG derivative |
| CAS | 2748638-78-8 |
| MW: | 277.4 D |
ab 101,00 €
