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Cimicoxib
Cimicoxib

Artikelnummer: TGM-T30937-100mg

Description: Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity. Target: COX. Smiles: ClC1=C(N(C=N1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC(F)=C(OC)C=C3. References: Kim TW, et al. Pharmacokinetic profiles of the novel COX-2 selective inhibitor cimicoxib in dogs. Vet...
Schlagworte: trade name: Cimalgex, UR8880, UR-8880
Anwendung: COX-2 inhibitor
CAS 265114-23-6
MW: 381.81 D
ab 39,00 €
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Cimicoxib
Cimicoxib

Artikelnummer: Cay10006295-1

Cimicoxib is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2 selectively over COX-1 (IC50s = 0.005 and 3.3 µM, respectively). It inhibits paw swelling by 93% in a rat model of adjuvant-induced arthritis when administered at a dose of 1 mg/kg. Cimicoxib (3 mg/kg, p.o.) inhibits carrageenan-induced...
Schlagworte: UR-8880, 4-[4-chloro-5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl]-benzenesulfonamide
Anwendung: COX-2 inhibitor
CAS 265114-23-6
MW: 381.8 D
ab 84,00 €
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