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MRS 1754
Artikelnummer: TGM-T16140-100mg
Description: MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor, exhibiting very low affinity for A1 and A3 receptors in both humans and rats. Target: Adenosine Receptor. Smiles: CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)Nc2ccc(cc2)C#N)cc1. References: Ji X, et al. [3H]MRS 1754, a...
| Anwendung: | Adenosine A2B receptor antagonist |
| CAS | 264622-58-4 |
| MW: | 486.52 D |
ab 40,00 €
MRS1754
Artikelnummer: Cay33501-10
MRS1754 is an adenosine A2B receptor antagonist (Ki = 1.97 nM). It is selective for adenosine A2B receptors over adenosine A1, A2A, and A3 receptors (Kis = 403, 503, and 570 nM, respectively). In vivo, MRS1754 (0.5-10 mg/kg) increases 28-day survival, as well as decreases peritoneal bacterial growth and plasma...
| Schlagworte: | N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide |
| Anwendung: | Adenosine A2B receptor antagonist |
| CAS | 264622-58-4 |
| MW: | 486.5 D |
ab 150,00 €
