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PR-619
PR-619

Artikelnummer: TGM-T1862-5mg

Description: PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor that inhibits USP2/4/5/7/8 (EC50=7.2/3.93/8.61/6.86/4.9 µM). PR-619 induces endoplasmic reticulum stress and activates autophagy. Target: Apoptosis, DUB, Autophagy. Smiles: Nc1nc(N)c(SC#N)cc1SC#N. References: Altun M, et al. Chem Biol,...
Schlagworte: PR 619, 2,6-Diamino-3,5-dithiocyanopyridine
Anwendung: DUB inhibitor
CAS 2645-32-1
MW: 223.28 D
ab 45,00 €
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PR-619
PR-619

Artikelnummer: Cay16276-5

PR-619 is a general inhibitor of deubiquitylating enzymes (DUBs), significantly reducing the activity of a panel of DUBs with EC50 values ranging from 5-20 µM. It is cell-permeable and reversible in its action. It is selective for DUBs over other proteases. PR-619 induces the accumulation of polyubiquitinated...
Schlagworte: 2,6-Diamino-3,5-dithiocyanopyridine, DUB Inhibitor V, thiocyanic acid, C,C'-(2,6-diamino-3,5-pyridinediyl) ester
Anwendung: DUB inhibitor
CAS 2645-32-1
MW: 223.3 D
ab 81,00 €
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PR-619
PR-619

Artikelnummer: LKT-P7000.1

Deubiquitinating enzyme inhibitor.
Anwendung: Deubiquitinating enzyme inhibitor
CAS 2645-32-1
MW: 223.27 D
ab 82,00 €
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