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BMS270394
Artikelnummer: TGM-T26846-1mg
Description: BMS270394 is a RARgamma agonist used in the study of breast cancer and dermatologic diseases. Target: Retinoid Receptor. Smiles: CC1(C)C=2C(=CC=C([C@H](C(NC3=C(F)C=C(C(O)=O)C=C3)=O)O)C2)C(C)(C)CC1. References: Klaholz BP, et al. Enantiomer discrimination illustrated by high-resolution crystal structures...
| Schlagworte: | BMS 270394, BMS 189961, BMS-270394 |
| Anwendung: | RARgamma agonist |
| CAS | 262433-54-5 |
| MW: | 399.46 D |
390,00 €
BMS 270394
Artikelnummer: Cay35576-1
BMS 270394 is an agonist of retinoic acid receptor gamma (RARgamma, EC50 = 30 nM in a transactivation assay) and the active enantiomer of BMS 189961 (Cay-29380). It is selective for RARgamma over RARbeta (EC50 = 400 nM) and is inactive at RARalpha. BMS 270394 synergizes with paclitaxel (Cay-10461) to inhibit the...
| Schlagworte: | 3-fluoro-4-[[(2R)-2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]-benzoic acid |
| Anwendung: | RARgamma agonist |
| CAS | 262433-54-5 |
| MW: | 399.5 D |
ab 150,00 €
