Zu "260264-93-5" wurden 2 Artikel gefunden!
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GI254023X
Artikelnummer: TGM-T7522-100mg
Description: GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the alpha-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells, potentially through inhibition of Notch1 activation. Target:...
| Schlagworte: | GI 254023X |
| Anwendung: | ADAM10 inhibitor |
| CAS | 260264-93-5 |
| MW: | 391.5 D |
ab 97,00 €
GI 254023X
Artikelnummer: Cay28284-1
GI 254023X is an inhibitor of the metalloproteinase-disintegrin ADAM10 (IC50 = 5.3 nM). It is selective for ADAM10 over ADAM17, matrix metalloproteinase-1 (MMP-1), and MMP-3 (IC50s = 541, 108, and 187 nM, respectively), but also inhibits MMP-9 and MMP-13 (IC50s = 2.5 and 1.1 nM, respectively). GI 254023X inhibits...
| Schlagworte: | GI 4023, SRI 028594,... |
| Anwendung: | ADAM10 inhibitor |
| CAS | 260264-93-5 |
| MW: | 391.5 D |
ab 78,00 €
