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AZD5305
Artikelnummer: TGM-T9165-100mg
Description: AZD5305 is a potent, selective and oral active PARP inhibitor. Target: PARP. Smiles: CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O
| Anwendung: | PARP1 inhibitor |
| CAS | 2589531-76-8 |
| MW: | 406.48 D |
ab 112,00 €
AZD 5305
Artikelnummer: Cay37769-10
AZD 5305 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1, IC50 = 0.003 µM). It is selective for PARP1 over PARP2, PARP3, PARP5a, and PARP6 (IC50s = 1.4, 3.4, >89, and 26 µM, respectively). AZD 5305 inhibits the proliferation of BRCA2-/- DLD-1 colorectal cancer cells (IC50 = 0.002 µM). It induces tumor...
| Schlagworte: | 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl-2-pyridinecarboxamide |
| Anwendung: | PARP1 inhibitor |
| CAS | 2589531-76-8 |
| MW: | 406.5 D |
ab 175,00 €
