Zu "256922-53-9" wurden 2 Artikel gefunden!
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CL075
Artikelnummer: TGM-T27034-1mg
Description: CL075 (3M002) is a selective TLR8 agonist with immunomodulatory activity, triggering the MyD88-dependent signaling pathway and activating NF-kappaB and IRF7 to elicit the production of inflammatory cytokines and type I interferon (IFN). Target: NF-kappaB, TLR, MyD88. Smiles: CCCc1nc2c(N)nc3ccccc3c2s1....
| Schlagworte: | CL-075, 3M002 |
| Anwendung: | TLR8 agonist |
| CAS | 256922-53-9 |
| MW: | 243.33 D |
ab 34,00 €
CL075
Artikelnummer: Cay37686-10
CL075 is a toll-like receptor 8 (TLR8) agonist. It induces NF-kappaB activation in a reporter assay using HEK293 cells expressing recombinant human TLR8 and TNF-alpha production in isolated human peripheral blood mononuclear cells (PBMCs) when used at concentrations ranging from 1 to 10 µM. In vivo, CL075 induces...
| Schlagworte: | 3M-002, 2-propyl-thiazolo[4,5-c]quinolin-4-amine |
| Anwendung: | TLR8 agonist |
| CAS | 256922-53-9 |
| MW: | 243.3 D |
ab 118,00 €
