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PBIT
PBIT

Artikelnummer: TGM-T16435-100mg

Description: PBIT inhibits JARID1B histone demethylase (IC50 of about 3 µM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 µM and 4.9 µM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes . Target: Histone Methyltransferase, Histone Demethylase. Smiles:...
Anwendung: JARID1B inhibitor
CAS 2514-30-9
MW: 241.31 D
ab 34,00 €
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PBIT
PBIT

Artikelnummer: Cay16272-5

Jumonji AT-rich interactive domain 1 (JARID1) demethylases mediate the removal of methyl groups from trimethylated lysine 4 on histone 3 (H3K4me3). PBIT is a reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 µM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively). It...
Schlagworte: 2-p-tolyl-1,2-Benzisothiazolin-3-one, 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one
Anwendung: JARID1B inhibitor
CAS 2514-30-9
MW: 241.3 D
ab 50,00 €
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