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Mesembrine
Artikelnummer: Cay21100-5
Mesembrine is an alkaloid that has been found in S. tortuosum and has serotonin (5-HT) reuptake inhibitory activity. It selectively binds to the 5-HT transporter (SERT, IC50 = 4.3 µg/ml) over a variety of receptors (IC50s = 148->750 µg/ml). Mesembrine inhibits the reuptake of 5-HT in vitro (Ki = 1.4 nM). It has...
| Schlagworte: | (-)-Mesembrine, Mesembranone, (3aS,7aS)-3a-(3,4-dimethoxyphenyl)octahydro-1-methyl-6H-indol-6-one |
| Anwendung: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.4 D |
ab 208,00 €
(-)-Mesembrine
Artikelnummer: TGM-T28019-10mg
Description: Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). Target: Others. Smiles: CN1[C@@]2([C@](CC1)(CCC(=O)C2)C3=CC(OC)=C(OC)C=C3)[H]. References: Krstenansky JL. Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacology. J...
| Schlagworte: | Mesembrin, Mesembrine, Mesembranone |
| Anwendung: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.37 D |
ab 375,00 €
