Zu "246020-68-8" wurden 2 Artikel gefunden!
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TRi-1
Artikelnummer: TGM-T5481-100mg
Description: TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy. Target: Others. Smiles: COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O. References: Stafford WC, et al. Irreversible inhibition of...
| Anwendung: | Irreversible TrxR1 inhibitor |
| CAS | 246020-68-8 |
| MW: | 328.73 D |
ab 66,00 €
Thioredoxin Reductase 1 Inhibitor 1
Artikelnummer: Cay31307-10
Thioredoxin reductase 1 inhibitor 1 (TRi-1) is an irreversible inhibitor of thioredoxin reductase 1 (TrxR1, IC50 = 0.012 µM). It inhibits TrxR1-induced reduction of Trx1 in a cell-free assay (IC50 = 4.3 µM). TRi-1 (10 µM) reduces the mitochondrial oxygen consumption rate in HCT116 colorectal cancer cells. It...
| Schlagworte: | TRi-1, TxnR1 Inhibitor 1, Txnrd1 Inhibitor 1, 2-[(4-chlorophenyl)sulfonyl]-6-methoxy-3-nitro-pyridine |
| Anwendung: | Irreversible TrxR1 inhibitor |
| CAS | 246020-68-8 |
| MW: | 328.7 D |
ab 249,00 €
