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YQ128
Artikelnummer: TGM-T13375-100mg
Description: YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM and exhibits significant anti-inflammatory activity. Target: Interleukin, NOD-like Receptor (NLR), NOD, IL Receptor. Smiles:...
| Anwendung: | NLRP3 inflammasome inhibitor |
| CAS | 2454246-18-3 |
| MW: | 545.11 D |
ab 51,00 €
YQ-128
Artikelnummer: Cay36451-1
YQ-128 is an inhibitor of the NOD-like receptor protein 3 (NLRP3) inflammasome (IC50 = 0.3 µM). It inhibits LPS- and ATP-induced IL-1beta release from isolated mouse peritoneal macrophages (IC50 = 1.59 µM). YQ-128 (10 mg/kg) inhibits LPS-induced IL-1beta production in wild-type but not Nlrp3-/- mice.Formal Name:...
| Schlagworte: | N-[(5-chloro-2-propoxyphenyl)methyl]-N-[2-[4-[(2-propyn-1-ylamino)sulfonyl]phenyl]ethyl]-3-thiopheneacetamide |
| Anwendung: | NLRP3 inflammasome inhibitor |
| CAS | 2454246-18-3 |
| MW: | 545.1 D |
ab 39,00 €
