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M4K2234
Artikelnummer: TGM-T74660-2mg
Description: M4K2234 (compound 26b), an ALK2 inhibitor, demonstrates selective inhibition of ALK2 and ALK5 with IC50 values of 5 nM and 2144 nM, respectively. Serving as a chemical probe for ALK1 and ALK2 protein kinases, M4K2234 holds potential for cancer research applications [1]. Target: Others. Smiles:...
| Anwendung: | ALK1 / ALK2 inhibitor |
| CAS | 2421141-51-5 |
| MW: | 462.56 D |
120,00 €
M4K2234
Artikelnummer: Cay41169-1
M4K2234 is an inhibitor of activin receptor-like kinase 1 (ALK1) and ALK2 (IC50s = 7 and 14 nM, respectively). M4K2234 is selective for ALK1 and ALK2 over ALK3, -4, -5, and -6 (IC50s = 168, 1,660, 1,950, and 88 nM, respectively), as well as 30 additional kinases at 1 µM, but does inhibit TRAF2- and NCK-interacting...
| Schlagworte: | 2-fluoro-6-methoxy-4-[4-methyl-5-[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-3-pyridinyl]-benzamide |
| Anwendung: | ALK1 / ALK2 inhibitor |
| CAS | 2421141-51-5 |
| MW: | 462.6 D |
ab 62,00 €
