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NEU
GDC-6036
Artikelnummer: Cay41852-1
GDC-6036 is a covalent inhibitor of K-Ras containing a glycine-to-cysteine substitution at position 12 (K-RasG12C). It decreases tumor volume in a PaCa-2 pancreatic cancer mouse xenograft model when administered at doses ranging from 1 to 100 mg/kg per day.Formal Name:...
| Schlagworte: | Divarasib, RG-6330,... |
| Anwendung: | Covalent K-RasG12C inhibitor |
| CAS | 2417987-45-0 |
| MW: | 622.1 D |
ab 136,00 €
Divarasib
Artikelnummer: TGM-T9972-100mg
Description: Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 µM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibits tumor cell growth. It is being investigated for use in solid tumors, including...
| Schlagworte: | GDC-6036 |
| Anwendung: | Targets GTPase KRas (KRAS, KRAS2) |
| CAS | 2417987-45-0 |
| MW: | 622.06 D |
ab 239,00 €
