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ADTL-EI1712
Artikelnummer: TGM-T38377-10mg
Description: ADTL-EI1712 is a dual inhibitor of ERK1 and ERK5 (IC50s = 40.43 and 64.5 nM, respectively).1It reduces ERK1 and ERK5 activity by 93.5% and 89.4%, respectively, but also inhibits ERK2 activity by 92.7%, in a panel of 100 kinases at 1 µM. ADTL-EI1712 inhibits proliferation of HL-60 and MKN74, but not...
| Schlagworte: | ADTL-EI1712 |
| Anwendung: | Dual ERK1 / ERK5 inhibitor |
| CAS | 2414916-45-1 |
| MW: | 505.44 D |
ab 154,00 €
ADTL-EI1712
Artikelnummer: Cay30602-1
ADTL-EI1712 is a dual inhibitor of ERK1 and ERK5 (IC50s = 40.43 and 64.5 nM, respectively). It reduces ERK1 and ERK5 activity by 93.5% and 89.4%, respectively, but also inhibits ERK2 activity by 92.7%, in a panel of 100 kinases at 1 µM. ADTL-EI1712 inhibits proliferation of HL-60 and MKN74, but not HeLa, cancer...
| Schlagworte: | 2-[(2-chlorobenzoyl)amino]-6-[[(2-chlorophenyl)amino]thioxomethyl]-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxamide |
| Anwendung: | Dual ERK1 / ERK5 inhibitor |
| CAS | 2414916-45-1 |
| MW: | 505.4 D |
ab 86,00 €
