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FT709
Artikelnummer: TGM-T63375-10mg
Description: FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM), a protein associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization, and circadian rhythms. Target: Others. Smiles:...
| Anwendung: | USP9X inhibitor |
| CAS | 2413991-74-7 |
| MW: | 498.51 D |
ab 198,00 €
FT709
Artikelnummer: Cay39971-1
FT709 is an inhibitor of ubiquitin-specific protease 9X (USP9X, IC50 = 82 nM). It is selective for USP9X over a panel of 20 deubiquitinases (IC50s = >25 µM for all). FT709 (10 µM) decreases the levels of the USP9X substrate centrosomal protein of 55 kDa (CEP55), as well as zinc-finger protein 598 (ZNF598), makorin 1...
| Schlagworte: | (2S)-1-[5-[(2,3-dihydro-1,4-dioxino[2,3-b]pyridin-7-yl)sulfonyl]-3,4,5,6-tetrahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-2-hydrox... |
| Anwendung: | USP9X inhibitor |
| CAS | 2413991-74-7 |
| MW: | 498.5 D |
ab 113,00 €
