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CU-76
Artikelnummer: TGM-T38329-5mg
Description: CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS, IC50= 0.24 µM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory...
| Anwendung: | cGAS inhibitor |
| CAS | 2400954-58-5 |
| MW: | 407.11 D |
709,00 €
CU-76
Artikelnummer: Cay31030-1
CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS, IC50 = 0.24 µM). It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 (IRF3, Cay-22811) in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases...
| Schlagworte: | methyl 4-amino-6-((3,5-difluoro-4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate |
| Anwendung: | cGAS inhibitor |
| CAS | 2400954-58-5 |
| MW: | 407.1 D |
ab 111,00 €
