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NEU
BAY-3827
Artikelnummer: Cay41448-10
BAY-3827 is an inhibitor of AMP-activated protein kinase (AMPK, IC50 = 1.4 nM at 10 µM ATP). It is selective for AMPK over Aurora A kinase, FMS-related tyrosine kinase 3 (FLT3), and c-Met (IC50s = 1,324, 124, and 788 nM, respectively), p90 ribosomal S6 kinase 2 (RSK2), RSK3, RSK4, p90 ribosomal S6 kinase 1 (MSK1),...
| Schlagworte: | N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl-benzamide |
| Anwendung: | AMPK inhibitor |
| CAS | 2377576-35-5 |
| MW: | 468.5 D |
ab 144,00 €
BAY-3827
Artikelnummer: TGM-T73350-100mg
Description: BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, demonstrating antiproliferative effects in an androgen-dependent prostate cancer model and inhibiting the phosphorylation of acetyl CoA carboxylase 1 (ACC-1). Target: AMPK, Acyltransferase. Smiles:...
| CAS | 2377576-35-5 |
| MW: | 468.53 D |
ab 51,00 €
