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ALSTERPAULLONE
ALSTERPAULLONE

Artikelnummer: TGM-T7426-100mg

Description: Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec. Target: CDK, GSK-3, Apoptosis. Smiles: [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1. References: Cui C , Wang Y , Wang Y , et al. Alsterpaullone, a Cyclin-Dependent Kinase...
Anwendung: CDK inhibitor
CAS 237430-03-4
MW: 293.28 D
ab 87,00 €
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Alsterpaullone
Alsterpaullone

Artikelnummer: Cay14428-1

Alsterpaullone is a derivative of kenpaullone (Cay-10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK3beta). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E,...
Schlagworte: 9-Nitropaullone, NSC 705701, 7,12-dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one
Anwendung: CDK inhibitor, GSK-3beta inhibitor
CAS 237430-03-4
MW: 293.3 D
ab 92,00 €
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Alsterpaullone
Alsterpaullone

Artikelnummer: AG-CR1-0036-M001

Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-3beta (glycogen synthase kinase-3beta) inhibitor, Apoptosis inhibitor, Apoptosis inducer, Angiogenesis inhibitor.
Schlagworte: 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one
Anwendung: CDK inhibitor
CAS 237430-03-4
MW: 293,3 D
ab 44,00 €
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Alsterpaullone
Alsterpaullone

Artikelnummer: LKT-A4577.1

Dark yellow powder. The most active paullone. It is a potent inhibitor of glycogen synthase kinase-3b and cyclin - dependent kinase 5/p25. It has been shown to induce apoptosis and promote loss in clonogenicity in the Jurkate cell line.
Anwendung: Kinase inhbitor
CAS 237430-03-4
MW: 293,28 D
ab 245,00 €
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