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K777
Artikelnummer: TGM-T15641-25mg
Description: K777 is a potent, orally active, and irreversible inhibitor of cysteine protease, functioning as a potent CYP3A4 inhibitor (IC50 = 60 nM) and a selective CCR4 antagonist, which inhibits chemotaxis. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypanosoma cruzi, and cathepsins B and...
| Schlagworte: | APC-3316 |
| Anwendung: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574.73 D |
ab 79,00 €
![K777 [K11777]](https://www.biomol.com/media/image/e7/bc/7c/AG-CR1-0158-M001_200x200.png "K777 [K11777]")
K777 [K11777]
Artikelnummer: AG-CR1-0158-M005
Solid. Soluble in DMSO. Insoluble in water. Potent, irreversible cysteine protease inhibitor, Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well, Suppresses particle-induced...
| Schlagworte: | K-777, K-11777, N-Pip-F-hF-VS Phenyl, N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl,... |
| Anwendung: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574,7 D |
ab 44,00 €
K777
Artikelnummer: Cay19114-1
K777 is a cysteine protease inhibitor. It inhibits human cathepsin S (Ki = 0.002 µM) and human cathepsin L (Ki = 0.05 µM), which cleaves the severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein, also known as the surface glycoprotein. K777 is selective for these proteases over human cathepsin K,...
| Schlagworte: | APC-3316, CRA-3316, K11777, MePip-Phe-hPhe-VSf,... |
| Anwendung: | Cysteine protease (CTSS, CTSK) inhibitor |
| CAS | 233277-99-1 |
| MW: | 574.7 D |
ab 70,00 €
