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NVP-DKY709
Artikelnummer: Cay41295-1
NVP-DKY709 is a degrader of Ikaros family zinc finger protein 2 (IKZF2) with a half-maximal degradation concentration (DC50) value of 4 nM. It is selective for IKZF2 over 8,656 other proteins, including IKZF1, IKZF3, and IKZF5, at 2.5 µM, but it does degrade IKZF4, which has the same zinc finger 2 beta-hairpin...
| Schlagworte: | 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-2,6-piperidinedione |
| Anwendung: | IKZF2 degrader |
| CAS | 2291360-73-9 |
| MW: | 417.5 D |
ab 67,00 €
NVP-DKY709
Artikelnummer: TGM-T9806-100mg
Description: NVP-DKY709 is a potent inhibitor of IKZF2 for the treatment of cancers. Target: Others. Smiles: O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)C4CCN(CC5=CC=CC=C5)CC4. References: Simone BONAZZI, et al. Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione...
| CAS | 2291360-73-9 |
| MW: | 417.5 D |
ab 97,00 €
