Zu "2288709-96-4" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
AZ32
Artikelnummer: TGM-T4443-100mg
Description: AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 µM for ATM in cells. Target: ATM/ATR. Smiles: CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1. References: Karlin J, et al. Orally Bioavailable and Blood-Brain...
| Anwendung: | ATM inhibitor |
| CAS | 2288709-96-4 |
| MW: | 328.37 D |
ab 51,00 €
AZ 32
Artikelnummer: Cay26380-1
AZ 32 is an inhibitor of ataxia-telangiectasia mutated (ATM) kinase (IC50 = 50s = 4.6 and >4.6 µM, respectively). AZ 32 enhances radiation-induced cytotoxicity in a panel of five human glioma cells expressing wild-type or mutant p53. It increases survival in a U87-281G glioma orthotopic mouse xenograft model, as...
| Schlagworte: | N-methyl-4-(6-phenylimidazo[1,2-a]pyrazin-3-yl)benzamide |
| Anwendung: | ATM inhibitor |
| CAS | 2288709-96-4 |
| MW: | 328.4 D |
ab 50,00 €
