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NDI-034858
Artikelnummer: TGM-T62902-100mg
Description: NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23. Target: IL Receptor, Tyrosine Kinases. Smiles:...
| Schlagworte: | NDI-03485, TAK-279 |
| Anwendung: | TYK2 inhibitor |
| CAS | 2272904-53-5 |
| MW: | 460.49 D |
ab 261,00 €
Zasocitinib
Artikelnummer: Cay35682-1
Zasocitinib is an inhibitor of tyrosine kinase 2 (TYK2). It selectively binds to the TYK2 Janus homology (JH2) domain (Kd = 0.0038 nM) over the JAK1 and JAK2 JH2 domains (Kds = 4,975 and 23,000 nM, respectively). Zasocitinib inhibits the production of chemokine (C-X-C motif) ligand 10 (CXCL10) induced by IFN-alpha...
| Schlagworte: | NDI-034858, TAK-279,... |
| Anwendung: | TYK2 inhibitor |
| CAS | 2272904-53-5 |
| MW: | 460.5 D |
ab 417,00 €
