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NEU
SBI-797812
Artikelnummer: Cay41526-10
SBI-797812 is an activator of nicotinamide phosphoribosyltransferase (Nampt). It increases nicotinamide (NMN) levels and prevents NAD+ feedback inhibition in a cell-free assay using recombinant human Nampt when used at a concentration of 2 µM. In vivo, SBI-797812 (20 mg/kg) increases liver levels of NAD+ but does...
| Schlagworte: | N-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N'-(4-pyridinylmethyl)-urea |
| Anwendung: | Nampt activator |
| CAS | 2237268-08-3 |
| MW: | 402.5 D |
ab 108,00 €
SBI-797812
Artikelnummer: TGM-T12854-100mg
Description: SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 µM). Target: NAMPT. Smiles: O=C(NCc1ccncc1)Nc1ccc(cc1)S(=O)(=O)N1CC2CCC(C1)O2. References: Gardell SJ , et al. Boosting NAD+ with a small molecule that activates NAMPT. Nat Commun. 2019 Jul 19,10(1):3241.
| CAS | 2237268-08-3 |
| MW: | 402.47 D |
ab 53,00 €
