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ONO 4817
Artikelnummer: TGM-T21814-1mg
Description: ONO-4817 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (MMPs). It effectively reduces the development of aortic intimal hyperplasia in...
| Anwendung: | MMP-2 / MMP-9 inhibitor |
| CAS | 223472-31-9 |
| MW: | 416.47 D |
ab 259,00 €
ONO-4817
Artikelnummer: Cay34058-1
ONO-4817 is an inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 0.5 and 0.8 nM, respectively, for the human enzymes). It is selective for MMP-2 and -9 over MMP-3 and -1 (IC50s = 26 and 2,500 nM, respectively). ONO-4817 (5 µg/ml) decreases bronchoalveolar lavage fluid (BALF) neutrophil infiltration...
| Schlagworte: | MMP Inhibitor V, N-[(1S,3S)-1-[(ethoxymethoxy)methyl]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxy-benzamide |
| Anwendung: | MMP-2 / MMP-9 inhibitor |
| CAS | 223472-31-9 |
| MW: | 416.5 D |
ab 142,00 €
