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AZD-7648
Artikelnummer: TGM-T7122-100mg
Description: AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity. Target: DNA-PK. Smiles: Cc1cc2ncnn2cc1Nc1ncc2n(C)c(=O)n(C3CCOCC3)c2n1. References: Maurice Raymond Verschoyle Finlay, et al. Amino-triazolopyridine compounds and their...
| Anwendung: | DNA-PK inhibitor |
| CAS | 2230820-11-6 |
| MW: | 380.4 D |
ab 34,00 €
AZD 7648
Artikelnummer: Cay28598-1
AZD 7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK, IC50 = 0.63 nM in an enzyme assay). It is selective for DNA-PK over TTK (IC50 = 5.012 µM), as well as JAK1, JAK2, JAK3, Aurora A, and Aurora B (IC50s = >10 µM for all). AZD 7648 reduces tumor growth in a FaDu ATM KO pharynx cancer mouse xenograft...
| Schlagworte: | 7,9-dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Anwendung: | DNA-PK inhibitor |
| CAS | 2230820-11-6 |
| MW: | 380.4 D |
ab 52,00 €
AZD-7648
Artikelnummer: LKT-A985128.1
DNA-PK inhibitor.
| Schlagworte: | AZD 7648, AZD7648 |
| Anwendung: | DNA-PK inhibitor |
| CAS | 2230820-11-6 |
| MW: | 380.41 D |
ab 121,00 €
