Zu "2225819-06-5" wurden 2 Artikel gefunden!
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BAY-2402234
Artikelnummer: TGM-T14501-100mg
Description: BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. Target: Dehydrogenase, DNA/RNA Synthesis. Smiles:...
| Anwendung: | DHODH inhibitor |
| CAS | 2225819-06-5 |
| MW: | 520.84 D |
ab 179,00 €
BAY-2402234
Artikelnummer: Cay33259-1
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 1.2 nM). It induces upregulation of the cell differentiation marker CD11b in MOLM-13 and HEL acute myeloid leukemia (AML) cells (EC50s = 3.16 and 0.96 nM, respectively) and inhibits the proliferation of nine leukemia cell lines (IC50s =...
| Schlagworte: | N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-4,5-dihydro-3-(hydroxymethyl)-5-oxo-1H-1,2,4-triazol-1-yl]-5-fluoro-2-[(1S)-2,2,2-t... |
| Anwendung: | DHODH inhibitor |
| CAS | 2225819-06-5 |
| MW: | 520.8 D |
ab 130,00 €
