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5,15-DPP
Artikelnummer: TGM-T21501-5mg
Description: 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist with IC50 values of 0.28 µM for STAT3 and 10 µM for STAT1 [1]. Target: Others. Smiles: c1cc2nc1cc1ccc([nH]1)c(-c1ccccc1)c1ccc(cc3ccc([nH]3)c2-c2ccccc2)n1
| Anwendung: | STAT3 dimerization inhibitor |
| CAS | 22112-89-6 |
| MW: | 462.54 D |
38,00 €
5,15-DPP
Artikelnummer: Cay16090-10
Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. 5,15-DPP is a cell-permeable porphyrin derivative that selectively binds STAT3 (Kd = 880 nM). This inhibits STAT3 dimerization via Src homology 2 (Sh2) domains (IC50 = 280...
| Schlagworte: | 5,15-Diphenylporphyrin, STAT3 Inhibitor VIII, 5,15-diphenyl-21H,23H-porphine |
| Anwendung: | STAT3 dimerization inhibitor |
| CAS | 22112-89-6 |
| MW: | 462.6 D |
ab 43,00 €
