Zu "2196204-23-4" wurden 2 Artikel gefunden!
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AZ1495
Artikelnummer: TGM-T14367-100mg
Description: AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL). Target: Haspin Kinase, CDK, IRAK. Smiles:...
| Anwendung: | IRAK4 inhibitor |
| CAS | 2196204-23-4 |
| MW: | 385.5 D |
ab 148,00 €
IRAK4 Inhibitor 28
Artikelnummer: Cay40167-1
IRAK4 inhibitor 28 is an inhibitor of IL-1 receptor-associated kinase 4 (IRAK4, IC50 = 0.005 µM). It is selective for IRAK4 over IRAK1, CDC-like kinase 1 (Clk1), and Clk3 (IC50s = 0.023, 0.05, and >1 µM, respectively) but does inhibit Clk2, Clk4, and haspin (IC50s = 0.005, 0.008, and 0.004 µM, respectively). IRAK4...
| Schlagworte: | IRAK-IN-28, N-[trans-4-(4-morpholinyl)cyclohexyl]-5-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Anwendung: | IRAK4 inhibitor |
| CAS | 2196204-23-4 |
| MW: | 385.5 D |
ab 78,00 €
