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ARN19874
Artikelnummer: TGM-T14321-10mg
Description: ARN19874 is a selective, reversible uncompetitive inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity, with an IC50 of approximately 34 µM[1]. Target: Others. Smiles: O=C1C=2C(=CC=C(S(NC3=CC=C(C=C3)C=4C=CN=CC4)(=O)=O)C2)NC(=O)N1. References: Castellani B, et al. Synthesis and...
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2190502-57-7 |
| MW: | 394.4 D |
ab 77,00 €
ARN19874
Artikelnummer: Cay24283-1
ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD, IC50 = 33.7 µM). It is selective for NAPD-PLD over carbonic anhydrase II, neutral endopeptidase, and angiotensin-converting enzyme (ACE) up to 50 µM. ARN19874 (50 µM) increases the levels of certain NAPE substrates and decreases...
| Schlagworte: | 1,2,3,4-tetrahydro-2,4-dioxo-N-[4-(4-pyridinyl)phenyl]-6-quinazolinesulfonamide |
| Anwendung: | NAPE-PLD inhibitor |
| CAS | 2190502-57-7 |
| MW: | 394.4 D |
ab 44,00 €
