Zu "2188236-41-9" wurden 2 Artikel gefunden!
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APS6-45
Artikelnummer: TGM-T8843-100mg
Description: APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity. Target: MAPK, Ras. Smiles: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(ccc3F)C(F)(C(F)(F)F)C(F)(F)F)cc2)ccn1. References: Sonoshita M, Scopton AP, Ung PMU, et al. A whole-animal platform to advance a clinical kinase inhibitor into new disease...
| Anwendung: | RET-M918T inhibitor, sorafenib |
| CAS | 2188236-41-9 |
| MW: | 548.39 D |
ab 73,00 €
APS6-45
Artikelnummer: Cay38417-1
APS6-45 is an inhibitor of RETM918T and a derivative of sorafenib (Cay-10009644, Cay-35612). It selectively binds to RETM918T over Eph tyrosine kinase receptor A8 (EphA8), p38delta, JNK2, and c-Src (Kds = 28, 410, 940, 1,500, and 1,700 nM, respectively), as well as a panel of over 60 kinases at 10 µM, but also binds...
| Schlagworte: | 4-[4-[[[[2-fluoro-5-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridine... |
| Anwendung: | RET-M918T inhibitor, sorafenib |
| CAS | 2188236-41-9 |
| MW: | 548.4 D |
ab 35,00 €
