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BX 471
Artikelnummer: Cay18503-1
The CC chemokine receptor-1 (CCR1), whose ligands include macrophage inflammatory protein-1alpha (MIP-1alpha), RANTES, and monocyte chemotactic protein-3 (MCP-3), has a central role in leukocyte trafficking and is highly expressed in certain autoimmune diseases. BX 471 is a nonpeptide CCR1 antagonist that has been...
| Schlagworte: | N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea |
| Anwendung: | CCR1 antagonist |
| CAS | 217645-70-0 |
| MW: | 434.9 D |
ab 61,00 €
BX471
Artikelnummer: TGM-T2375-100mg
Description: BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist. Target: CCR. Smiles: C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1NC(N)=O. References: Liang M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol...
| Schlagworte: | BX 471, BX-471, ZK-811752 |
| CAS | 217645-70-0 |
| MW: | 434.89 D |
ab 33,00 €
