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NEU
K-604 (hydrochloride)
Artikelnummer: Cay41119-1
K-604 is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1, IC50 = 0.45 µM). It is selective for ACAT-1 over ACAT-2 (IC50 = 102.85 µM). K-604 reduces foaming of J774 macrophages (IC50 = 0.026 µM) and reduces cholesterol esterification in monocyte-derived macrophages (IC50 = 0.068 µM). It...
| Schlagworte: | 4-[2-(1H-benzimidazol-2-ylthio)ethyl]-N-[6-methyl-2,4-bis(methylthio)-3-pyridinyl]-1-piperazineacetamide, dihydrochloride |
| Anwendung: | ACAT-1 inhibitor |
| CAS | 217094-32-1 |
| MW: | 575.6 D |
ab 48,00 €
K-604 dihydrochloride
Artikelnummer: TGM-T11733-100mg
Description: K-604 dihydrochloride, a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor, exhibits an IC50 of 0.45±0.06 µM. Target: Acyltransferase. Smiles: Cl.Cl.CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1. References: Ikenoya M, et al. A selective ACAT-1 inhibitor, K-604, suppresses...
| CAS | 217094-32-1 |
| MW: | 575.64 D |
ab 51,00 €
