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SNDX-5613
Artikelnummer: TGM-T12943-100mg
Description: SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias. Target: Epigenetic Reader Domain, Histone Methyltransferase. Smiles:...
| Anwendung: | Targets menin (MEN1, MNN1) |
| CAS | 2169919-21-3 |
| MW: | 630.82 D |
ab 67,00 €
SNDX-5613
Artikelnummer: Cay40758-10
SNDX-5613 is a derivative of VTP-50469 (Cay-40759), an inhibitor of the protein-protein interaction between menin and mixed-lineage leukemia 1 (MLL1), also known as lysine methyltransferase 2A (KMT2A). It inhibits the growth of patient-derived acute myeloid leukemia (AML) cells expressing the gene encoding upstream...
| Schlagworte: | Revumenib,... |
| Anwendung: | VTP-50469 (MLL1-menin-interaction inhibitor) derivative |
| CAS | 2169919-21-3 |
| MW: | 630.8 D |
ab 163,00 €
