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VTP50469
Artikelnummer: TGM-T13336-100mg
Description: VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity. Target: Epigenetic Reader Domain, Histone Methyltransferase, Apoptosis. Smiles:...
| Anwendung: | Menin-MLL1 fusion protein interaction inhibitor |
| CAS | 2169916-18-9 |
| MW: | 630.82 D |
ab 175,00 €
VTP-50469
Artikelnummer: Cay40759-10
VTP-50469 is an inhibitor of the protein-protein interaction between menin and mixed lineage leukemia 1 (MLL1) fusion proteins (Ki = 0.104 nM). It selectively inhibits the growth of ten leukemia cell lines expressing MLL1 fusion proteins (IC50s = 13-37 nM) over HL-60 , K562, and Reh leukemia cells expressing...
| Schlagworte: | 5-fluoro-N,N-bis(1-methylethyl)-2-[[4-[7-[[trans-4-[(methylsulfonyl)amino]cyclohexyl]methyl]-2,7-diazaspiro[3.5]non-2-yl]-... |
| Anwendung: | Menin-MLL1 fusion protein interaction inhibitor |
| CAS | 2169916-18-9 |
| MW: | 630.8 D |
ab 285,00 €
